With my Health Coordinator’s
hat on, I am delighted with the following press release from the Kennel
Club.
At the request of the Keeshond
Breed Clubs, the Kennel Club has recently approved an official DNA
testing scheme for primary hyperparathyroidism (PHPT)
The test is offered by Cornell
University in America and more information can be obtained direct
from them at http://www.vet.cornell.edu/labs/goldstein/.
As copies of test results cannot
be sent directly to the Kennel Club by the laboratory, the owner of
a dog would be required to submit a copy of their dog’s result
if they wish the KC to record the DNA status.
Once the test result has been
added to the dog’s details on the registration database, it
will trigger the publication of the test result in the next available
Breed Records Supplement, and the result will also appear on any new
registration certificate issued for the dog and on the registration
certificates of any future progeny of the dog. Further the result
for each individual dog will also be available to view on the Kennel
Club’s Dog Health Test Search tool and also the collective results
for all those received will be found at www.thekennelclub.org.uk/item/315
When submitting a copy of the
DNA certificate, if the owner includes the original registration certificate
for the dog (not a copy), a new registration certificate will be issued,
with the DNA result on it, free of charge. Owners who have dogs which
are classed as hereditarily clear (negative by descent) can also have
their dog’s registration certificate updated free of charge
providing that they too send the original registration certificate
to us. Please note that we can only update a hereditarily clear status
providing the results for both parents are already recorded.
Please send the DNA test certificates
and registration certificates to the Health & Breeder Services
Department, The Kennel Club, 1 – 5 Clarges Street, Piccadilly,
London W1J 8AB. Alternatively test certificates can be faxed to 0207
518 1028 or emailed to Gary Johnson at gary.johnson@thekennelclub.org.uk.
For further information on this scheme please contact Professor Jeff
Sampson at jeff.sampson@thekennelclub.org.uk.
All you need to do is to send
a copy of your dog/s test certificate/s to the KC; if you want your
dog/s registration form/s amending then send the original in at the
same time. It will just cost you the price of a stamp. This will make
life so much easier once all our tested dogs are on the KC’s
data base. The clubs open registers are becoming somewhat unwieldy;
as the majority of dogs registered now are negative by descent, quite
often for several generations. So please, please send a copy of your
dog/s certificate/s off ASAP, as until all the tested dogs are on
the data base, the negative by descents can’t be issued. These
are produced automatically; as gene negative tested sires & dams
are recorded, all their progeny will be listed as negative by descent
(hereditarily clear) and their progeny too. This also applies to our
dogs that are no longer with us; if they were tested & bred from;
their certificates also need to be sent to the KC.
For those of you that have a
dog from abroad it is slightly more complicated as the KC needs written
permission (and a copy of the test certificate) from the person who
actually owned the dog at the time of testing.
If are still unsure of what to do or you have any queries,
you can contact me anytime at health@north-of-england-keeshond-club.co.uk
CLICK
HERE TO VIEW THE STATUS OF AN INDIVIDUAL DOG
CLICK
HERE TO VIEW THE KENNEL CLUB'S KEESHOND PHPT REGISTER
F.A.Q.& A.
So what do you do if your Keeshond hasn’t been tested? First
of all - don’t panic! It would be nice to think that eventually
all breeders will put their dogs’ status on this open register;
so you could look up your dog’s sire and dam or even grand parents.
Until that happens though, if you wish to know, you can either contact
the breeder of your Keeshond, ask if the parents have been tested
and what the results are or you can have him/her tested yourself.
A gene negative dog mated to a gene negative bitch will produce puppies
that are gene negative by descent.
A gene negative by descent dog mated to a gene negative by descent
bitch will produce puppies that are also gene negative by descent.
There is no carrier status. A dog is either negative or positive for
the affected gene.
It only takes one copy of the defective gene to pass the disease on
to the offspring.
A gene positive dog mated to a gene negative bitch (or vice versa)
will produce a litter which could contain puppies that are all gene
negative, puppies that are all gene positive or a mixture of both
gene negative and positive puppies. There is no way of predetermining
the outcome; it is all in the luck of the draw. The status of any
puppies from such a mating can only be determined by testing for the
defective gene. In the long term if you were to repeat the above mating
until you had produced 100 puppies or more, statistically, 50% of
the offspring will have one copy of the defective gene and 50% will
not.
A gene positive dog mated to a gene positive bitch will produce a
litter in which statistically, if 100 puppies were born, 50% of the
offspring will have one copy of the defective gene (gene positive),
25% will have two copies of the normal gene (gene negative) and 25%
will have two copies of the defective PHPT gene. Based on research,
it appears that embryos in this last group with two copies of the
defective gene may actually not survive in utero, resulting in smaller
litter sizes for this type of breeding. This means that, like the
example above, the litter could contain puppies that are all gene
negative, puppies that are all gene positive or a mixture of both
gene negative and positive puppies. There is no way of predetermining
the outcome, the status of any puppies from such a mating can only
be determined by testing for the defective gene. Again, it is all
in the luck of the draw.
If, for example, a bitch is gene negative (either tested
or by descent) and two of her offspring have been tested gene negative;
it doesn’t automatically mean that the sire is gene negative,
unless he has been tested or is negative by descent. If for any reason
the sire hasn’t been tested and the status of the bitch is known
(or vice versa) then the puppies from that mating will have to be
tested.
If you are unlucky enough to have a Keeshond that has tested gene
positive, this gives you an unprecedented opportunity to use this
knowledge to give him/her the best care possible. Begin to monitor
the calcium level on a regular schedule, preferably once a year starting
around the age of four, so that you may catch the disease in its earliest
stages, before potential complications occur. You have time to plan
ahead and seek out qualified, skilled care in advance. PHPT affects
older Keeshonden with what is known as ‘age dependent penetrance.’
This means that the test does not identify clinical disease at the
time of testing; it indicates the presence of the defective gene,
or the genetic potential to develop the disease later in life. The
vast majority of Keeshonden with the defective gene will develop PHPT
if they live long enough, although they could die earlier from another
cause, for example cancer.
DOGS FROM ABROAD
| GERMANY |
GENE NEGATIVE
- TESTED |
GENE NEGATIVE
BY DESCENT |
GENE POSITIVE |
Alten Nierstal Patrick vom
Deisterland Caecilia aus dem
Deisterland Calypso aus dem
Eternal Heartbreaker's Alice
German Grey Shadow's Bodyguard
German Grey Shadow's Cody
German Grey Star's Angel
German Grey Star's Dream of Life
German Grey Star's Gipsy
German Grey Star's Int. Tommy
German Grey Star's Jolly
German Grey Star's Kimba
German Grey Star's Lacy
Hochkirchen Donatus von
Hochkirchen Findus von
Larchenhohe Bongo von der
Okerquelle Aisha-Alpina von der
|
German Grey Star's Henry
German Grey Star's Houston
German Grey Star's Harmony at Rufcharm
German Grey Star's Happy Hope
German Grey Star's Hexi
German Grey Star's Highlight at Venway
German Grey Star's Lasko
German Grey Star's Leijona
German Grey Star's Lucky
German Grey Star's Lucky Lady
German Grey Star's Luna
Scharfenstein Alex vom
Scharfenstein Alf vom
Scharfenstein Andy vom
Scharfenstein Arko vom
Scharfenstein Arras vom
Scharfenstein Asco vom
Scharfenstein Aischa vom
Scharfenstein Ayke vom
Scharfenstein Benjy vom
Scharfenstein Balu vom
Scharfenstein Berry vom
Scharfenstein Bodo vom
Scharfenstein Bongo vom
Scharfenstein Beauty vom
Scharfenstein Brixi vom
Scharfenstein Casar vom
Scharfenstein Charly vom
Scharfenstein Chico vom
Scharfenstein Cliff vom
Scharfenstein Candie vom
Scharfenstein Chila vom
Scharfenstein Chrysa vom
Scharfenstein Cendrine vom
Scharfenstein Curly vom
|
|
| NORWAY |
GENE NEGATIVE - TESTED |
GENE NEGATIVE BY DESCENT |
GENE POSITIVE |
Arctic Kees Addicted To Love
Arctic Kees All The Man That I Need
Clandara She’s The One-Nz
Clandara Silver Starlight-Nz
Dein Hards Attention Please
Dein Hards Day By Day
Fuzzie's Believe It or Not
Krohnaugens Cherry
Slettvolva's Sita
Suburban's Heronna |
Arctic Kees A Bit O’ My Heart
Arctic Kees Above The Law
Arctic Kees Affair V Alten Nierstal
Arctic Kees Ain’t No Doubt
Arctic Kees Another Level
Silver Done TheTrick Infinity
Silver Line
Infinity Bright Star
Infinity Silver Star
Infinity The Following Sea
Infinity SnowQueen
Infinity Love Child
Infinity Dancing with Silver |
Fuzzie's Blazing Star
Lohamra's Waltzing Matilda |
| SWEDEN |
GENE NEGATIVE - TESTED |
GENE NEGATIVE BY DESCENT |
GENE POSITIVE |
Bella Bonita D´Arlande
Elzwiks Ellie
Fannyfay Del Monte Dragnone
Suitkees Parle In Goud
Teutons Xclusive Candy
Toddhus Afrodite
Unda Marina My Funny Valentine |
Dungens Born To Be Wild
Dungens Born To Run
Dungens Belive In Love
Dungens Brave New Love
Dungens Baby Love Fayana
Dungens Elektra
Dungens Foxy Lady For Beauwood
Dungens Heaven Can Wait
Dungens Hot Shot
Dungens Heaven's On Fire
Dungens Hello Kitty
Dungens Hungry Eyes
Himlagårdens Hippo Hero
Himlagårdens Hicco Harpo
Himlagårdens Higgo Haldo
Himlagårdens Hippy Hilda
Himlagårdens Heppy Heja
Himlagårdens Happy Hailey
Himlagårdens Henny Hedda
Himlagårdens Honny Hope
Himlagårdens Izzo Isak
Himlagårdens Izza Ixi
Himlagårdens Izzy Itzi
Himlagårdens Izzi Iza |
Morgonstjärnans Geischa |
RUSSIA |
GENE NEGATIVE - TESTED |
GENE NEGATIVE BY DESCENT |
GENE POSITIVE |
| |
Russkoe Serebro Posh Totty at Cillakees |
|